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From Korean Salmon to Global Beauty: The Story of Rejuran
Health & Beauty

From Korean Salmon to Global Beauty: The Story of Rejuran

Dec 12, 2025

Modern interior of the VS LINE clinic with its logo.

Hello, this is VS Line Clinic Gangnam.

Seoul's first snow has already fallen. In this weather, prolonged exposure to cold winds can easily sensitize skin and leave it dehydrated and dull. 🥲

You're probably searching for various skincare methods for seasonally sensitive skin. Today, we'd like to introduce Rejuran Healer—a procedure receiving tremendous love both domestically and internationally.

Rejuran Healer promotes the skin's natural recovery to elevate overall skin condition.

Did you know this is one of K-beauty’s signature procedures? 😉

 

Korean-Developed 'Rejuran' Goes Global

This story begins with a company called Pharmaresearch. Founded in 1993, the company initially started with pharmaceutical consulting, importing, and sales. Building on this expertise, they began their own R&D in 2011.

📌 Gangneung's Salmon Becomes K-Beauty

At the time, Pharmaresearch was importing and selling a medicine called 'Placentex'—a drug developed by an Italian company using polydeoxyribonucleotide (PDRN) extracted from trout sperm.

This PDRN promotes cell regeneration and was developed as an orthopedic prescription for spinal discs, frozen shoulder, and tennis elbow.

Pharmaresearch wanted to develop this ingredient directly in Korea. Notably, the company's founder's hometown was Gangneung, Gangwon Province—Korea's largest salmon-spawning ground. 🐟

So they developed a Korean pharmaceutical using salmon sperm similar to that of trout.

📌 From Orthopedic Prescriptions to Skin Treatments

The company developed various products containing salmon-derived PDRN: wound-healing supplements, eye drops, knee-joint injections, and 'Rejuran'—a facial wrinkle-improvement injection.

Rejuran's reputation as a leading skin improvement injection is now spreading worldwide. Thanks to this, Pharmaresearch's export revenue has been growing year on year. 💸

📌 PDRN: Highly Stable DNA Fragments

'PDRN' refers to a substance made by cutting DNA into specific sizes.

Salmon have DNA with a base composition similar to humans. Therefore, salmon-derived PDRN is evaluated as a safe substance with virtually no foreign body reactions.

The core of 'Rejuran' lies in activating skin-healing abilities to improve the dermal layer environment and restore skin structure. Simply put, it thickens the dermal layer to make skin healthier, increases skin elasticity, and restores skin damaged by aging, UV rays, etc., to its original state.


Different Rejuran Healers for Different Areas

(Source: rejuran.co.kr)

Rejuran Healer, which helps with wound recovery, promotes cell growth, and increases skin elasticity and collagen, comes in several types—each with slightly different specialized effects!

💉 Rejuran I: Eye Area Wrinkle Specialist

Rejuran I is a milder version of Rejuran Healer. It's suitable when you want to focus on the under-eyes, eyelids, and eye wrinkles rather than the entire face.

💉 Rejuran HB: Comprehensive Skin Booster

Rejuran HB is also called premium Rejuran. HB stands for Hydro Booster, and this treatment contains PN ingredient and moisturizing hyaluronic acid in a 1:1 ratio. Therefore, this treatment is a comprehensive skin booster capable of not only skin regeneration but also moisture and hydration improvement.

Additionally, it has much less pain than other Rejuran treatments, making it suitable for those sensitive to pain.

💉 Rejuran S: Scar Improvement Specialist

Rejuran S is a product specialized for improving acne scars, depressed wounds, and other scars. It has higher viscosity and smaller volume than regular Rejuran, making it suitable for scar use.

It particularly helps fundamentally improve scars by supporting new tissue generation in depressed scars.

 

When to Get Rejuran Healer!

The period when Rejuran procedure effects truly appear is, on average, 3-7 days later. This is when Rejuran stimulates dermal layer cells to induce collagen and elastin production. Through this, you'll gradually notice improvement not only in skin elasticity but also in overall skin condition. 🤗

🌟 Post-Treatment Changes

  • Immediately after to day 3: Embossing phenomenon, redness, bruising may occur at injection sites
  • Within one month after treatment: Minimal pore improvement, skin surface and tone refinement, experiencing unique translucency of glass skin, improved skin elasticity and density
  • 3+ treatments at 2-4 week intervals recommended: While one session has effects, repeated treatments are more effective

🌟 Consider Rejuran When:

  • Aging concerns: Want to improve wrinkles, thinning, dryness, loss of elasticity, etc.
  • Dry skin: Severe inner dryness or skin dulled by UV rays, dry winter, heating, etc.
  • Uneven skin texture: Want to improve dull or uneven skin texture and add radiance
  • Sensitive skin: Want to calm sensitized skin and fundamentally increase regenerative power

=

Skin naturally loses elasticity and becomes easily dry over time. Rejuran Healer is loved worldwide because it's not just a surface treatment, but a therapeutic approach that elevates the skin's own regenerative power.

Interested in treatments that cultivate healthy skin? Visit VS Line Clinic Gangnam for accurate diagnosis and personalized 1:1 care plans.

We will be with you so your skin can always shine healthily. Thank you. 😊

 


  • Author: VS Line Clinic Gangman
  • Editor : Sia

Tags: Aesthetic, Clinic, Dermatology
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